2KNC

Platelet integrin ALFAIIB-BETA3 transmembrane-cytoplasmic heterocomplex

2KNC の概要

• エントリーDOI: 10.2210/pdb2knc/pdb
• NMR情報: BMRB: 16496
• 分子名称: Integrin alpha-IIb, Integrin beta-3 (2 entities in total)
• 機能のキーワード: integrin, transmembrane signaling, protein structure, cell adhesion, cleavage on pair of basic residues, disease mutation, disulfide bond, glycoprotein, membrane, pyrrolidone carboxylic acid, receptor, transmembrane, host-virus interaction, phosphoprotein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 14832.34

構造登録者

Yang, J.,Ma, Y.,Page, R.C.,Misra, S.,Plow, E.F.,Qin, J. (登録日: 2009-08-20, 公開日: 2009-09-29, 最終更新日: 2023-06-14)

• 主引用文献: Yang, J.,Ma, Y.Q.,Page, R.C.,Misra, S.,Plow, E.F.,Qin, J.; Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.; Proc.Natl.Acad.Sci.USA, 106:17729-17734, 2009; PubMed: 19805198; DOI: 10.1073/pnas.0909589106

実験手法

SOLUTION NMR