2KI6

The FGF1-S100A13-C2A hetero-hexameric complex structure: A component in the non-classical pathway for FGF1 secretion

2KI6 の概要

• エントリーDOI: 10.2210/pdb2ki6/pdb
• 分子名称: Synaptotagmin-1, Heparin-binding growth factor 1, Protein S100-A13, ... (4 entities in total)
• 機能のキーワード: fgf1-s100a13-c2a hetero-hexameric complex, fgf1, s100a13, c2a, calcium, cell junction, cytoplasmic vesicle, glycoprotein, lipoprotein, membrane, metal-binding, palmitate, phosphoprotein, synapse, transmembrane, acetylation, alternative splicing, angiogenesis, developmental protein, differentiation, growth factor, heparin-binding, mitogen, polymorphism, protein transport
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein: P21579; Secreted: P05230; Cytoplasm: Q99584 Q99584
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 82781.22

構造登録者

Krishna, S.M.,Rani, S.G.,Yu, C. (登録日: 2009-04-28, 公開日: 2010-03-09, 最終更新日: 2011-07-13)

• 主引用文献: Mohan, S.K.,Rani, S.G.,Yu, C.; The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion.; J.Biol.Chem., 285:15464-15475, 2010; PubMed: 20220137; DOI: 10.1074/jbc.M109.066357

実験手法

SOLUTION NMR