2KFT

NMR Solution structure of the first PHD finger domain of human Autoimmune Regulator (AIRE) in complex with Histone H3(1-20Cys) Peptide

2KFT の概要

• エントリーDOI: 10.2210/pdb2kft/pdb
• NMR情報: BMRB: 16878
• 分子名称: Autoimmune regulator, Histone H3, ZINC ION (3 entities in total)
• 機能のキーワード: phd finger, histone code, aire, apeced, transcription, alternative splicing, cytoplasm, disease mutation, dna-binding, metal-binding, nucleus, phosphoprotein, polymorphism, transcription regulation, zinc, zinc-finger, chromosomal protein, nucleosome core, transcription-protein binding complex, transcription/protein binding
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: O43918
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8444.36

構造登録者

Chakravarty, S.,Zeng, L.,Zhou, M. (登録日: 2009-02-27, 公開日: 2009-04-28, 最終更新日: 2024-05-22)

• 主引用文献: Chakravarty, S.,Zeng, L.,Zhou, M.M.; Structure and Site-Specific Recognition of Histone H3 by the PHD Finger of Human Autoimmune Regulator.; Structure, 17:670-679, 2009; PubMed: 19446523; DOI: 10.1016/j.str.2009.02.017

実験手法

SOLUTION NMR