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2K8U

Solution NMR structure of trans-4-hydroxynonenal derived dG adduct of (6S,8R,11S)-configuration matched with dC

Summary for 2K8U
Entry DOI10.2210/pdb2k8u/pdb
Related2K8T
Descriptor5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DCP*DGP*DCP*DTP*DAP*DGP*DC)-3', (2S,5R)-5-pentyltetrahydrofuran-2-ol (3 entities in total)
Functional Keywordshne-dg (6s, 8r, 11s), hne derived dg adduct, trans-4-hydroxynonenal, dna
Total number of polymer chains2
Total formula weight7485.02
Authors
Huang, H.,Wang, H.,Qi, N.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P. (deposition date: 2008-09-23, release date: 2008-11-04, Last modification date: 2022-03-16)
Primary citationHuang, H.,Wang, H.,Qi, N.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P.
The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence.
Biochemistry, 47:11457-11472, 2008
Cited by
PubMed: 18847226
DOI: 10.1021/bi8011143
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

건을2024-03-27부터공개중

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