2K42
Solution Structure of the GTPase Binding Domain of WASP in Complex with EspFU, an EHEC Effector
Summary for 2K42
Entry DOI | 10.2210/pdb2k42/pdb |
NMR Information | BMRB: 16824 |
Descriptor | Wiskott-Aldrich syndrome protein, ESPFU (2 entities in total) |
Functional Keywords | wasp, espfu, gbd, autoinhibition, cytoplasm, cytoskeleton, disease mutation, phosphoprotein, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton: P42768 |
Total number of polymer chains | 2 |
Total formula weight | 12199.59 |
Authors | Cheng, H.-C.,Skehan, B.M.,Campellone, K.G.,Leong, J.M.,Rosen, M.K. (deposition date: 2008-05-27, release date: 2008-07-22, Last modification date: 2024-05-29) |
Primary citation | Cheng, H.C.,Skehan, B.M.,Campellone, K.G.,Leong, J.M.,Rosen, M.K. Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF(U). Nature, 454:1009-1013, 2008 Cited by PubMed: 18650809DOI: 10.1038/nature07160 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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