2K2U
NMR Structure of the complex between Tfb1 subunit of TFIIH and the activation domain of VP16
Summary for 2K2U
| Entry DOI | 10.2210/pdb2k2u/pdb |
| Descriptor | RNA polymerase II transcription factor B subunit 1, Alpha trans-inducing protein (2 entities in total) |
| Functional Keywords | vp16, tfiih, tfb1, activation, transcription, ph domain, protein structure complex, dna damage, dna repair, nucleus, transcription regulation, dna-binding |
| Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
| Cellular location | Nucleus: P32776 Virion tegument: P04486 |
| Total number of polymer chains | 2 |
| Total formula weight | 16720.76 |
| Authors | Langlois, C.,Mas, C.,Di Lello, P.,Miller Jenkins, P.M.,Legault, J.,Omichinski, J.G. (deposition date: 2008-04-11, release date: 2008-08-12, Last modification date: 2021-10-20) |
| Primary citation | Langlois, C.,Mas, C.,Di Lello, P.,Jenkins, L.M.,Legault, P.,Omichinski, J.G. NMR Structure of the Complex between the Tfb1 Subunit of TFIIH and the Activation Domain of VP16: Structural Similarities between VP16 and p53. J.Am.Chem.Soc., 130:10596-10604, 2008 Cited by PubMed: 18630911DOI: 10.1021/ja800975h PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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