2K2U

NMR Structure of the complex between Tfb1 subunit of TFIIH and the activation domain of VP16

2K2U の概要

• エントリーDOI: 10.2210/pdb2k2u/pdb
• 分子名称: RNA polymerase II transcription factor B subunit 1, Alpha trans-inducing protein (2 entities in total)
• 機能のキーワード: vp16, tfiih, tfb1, activation, transcription, ph domain, protein structure complex, dna damage, dna repair, nucleus, transcription regulation, dna-binding
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast); 詳細
• 細胞内の位置: Nucleus: P32776; Virion tegument: P04486
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 16720.76

構造登録者

Langlois, C.,Mas, C.,Di Lello, P.,Miller Jenkins, P.M.,Legault, J.,Omichinski, J.G. (登録日: 2008-04-11, 公開日: 2008-08-12, 最終更新日: 2021-10-20)

• 主引用文献: Langlois, C.,Mas, C.,Di Lello, P.,Jenkins, L.M.,Legault, P.,Omichinski, J.G.; NMR Structure of the Complex between the Tfb1 Subunit of TFIIH and the Activation Domain of VP16: Structural Similarities between VP16 and p53.; J.Am.Chem.Soc., 130:10596-10604, 2008; PubMed: 18630911; DOI: 10.1021/ja800975h

実験手法

SOLUTION NMR