2K0U

High Resolution Solution NMR Structures of Oxaliplatin-DNA Adduct

Summary for 2K0U

• Entry DOI: 10.2210/pdb2k0u/pdb
• Related: 2K0T 2K0V 2K0W
• Descriptor: DNA (5'-D(*DCP*DCP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DTP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DAP*DGP*DAP*DCP*DCP*DAP*DGP*DAP*DGP*DG)-3'), CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II) (3 entities in total)
• Functional Keywords: oxaliplatin-dna adduct, dna
• Total number of polymer chains: 2
• Total formula weight: 7636.05

Authors

Bhattacharyya, D.,King, C.L.,Chaney, S.G.,Campbell, S.L. (deposition date: 2008-02-15, release date: 2009-02-03, Last modification date: 2011-08-31)

• Primary citation: Bhattacharyya, D.,Ramachandran, S.,Sharma, S.,Pathmasiri, W.,King, C.L.,Baskerville-Abraham, I.,Boysen, G.,Swenberg, J.A.,Campbell, S.L.,Dokholyan, N.V.,Chaney, S.G.; Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links.; Plos One, 6:e23582-e23582, 2011; PubMed: 21853154; DOI: 10.1371/journal.pone.0023582

Experimental method

SOLUTION NMR