2JPR
Joint refinement of the HIV-1 CA-NTD in complex with the assembly inhibitor CAP-1
Summary for 2JPR
Entry DOI | 10.2210/pdb2jpr/pdb |
Related | 2PWM 2PWO 2PXR |
Descriptor | Gag-Pol polyprotein, 1-(3-chloro-4-methylphenyl)-3-{2-[({5-[(dimethylamino)methyl]-2-furyl}methyl)thio]ethyl}urea (2 entities in total) |
Functional Keywords | cap-1, capsid, hiv-1, assembly inhibitor, viral protein |
Biological source | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497 |
Total number of polymer chains | 1 |
Total formula weight | 16499.42 |
Authors | Kelly, B.N.,Kyere, S.,Kinde, I.,Tang, C.,Howard, B.R.,Robinson, H.,Sundquist, W.I.,Summers, M.F.,Hill, C.P. (deposition date: 2007-05-22, release date: 2007-10-09, Last modification date: 2022-03-09) |
Primary citation | Kelly, B.N.,Kyere, S.,Kinde, I.,Tang, C.,Howard, B.R.,Robinson, H.,Sundquist, W.I.,Summers, M.F.,Hill, C.P. Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein J.Mol.Biol., 373:355-366, 2007 Cited by PubMed: 17826792DOI: 10.1016/j.jmb.2007.07.070 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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