2JGY
The crystal structure of human orotidine-5'-decarboxylase domain of human uridine monophosphate synthetase (UMPS)
Summary for 2JGY
Entry DOI | 10.2210/pdb2jgy/pdb |
Descriptor | UMP SYNTHASE (2 entities in total) |
Functional Keywords | transferase, glycosyltransferase, alternative splicing, lyase, polymorphism, decarboxylase, disease mutation, tim barrel dimer, orotidine-5'-decarboxylase, multifunctional enzyme, pyrimidine biosynthesis |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 61262.46 |
Authors | Moche, M.,Ogg, D.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-Schiavone, L.,Johansson, I.,Karlberg, T.,Kosinska, U.,Kotenyova, T.,Lehtio, L.,Nilsson, M.E.,Nyman, T.,Persson, C.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Uppenberg, J.,Upsten, M.,Thorsell, A.G.,van den Berg, S.,Weigelt, J.,Nordlund, P.,Structural Genomics Consortium (SGC) (deposition date: 2007-02-16, release date: 2007-03-06, Last modification date: 2023-12-13) |
Primary citation | Moche, M.,Flodin, S.,Nyman, T.,Stenmark, P.,Nordlund, P. The Crystal Structure of Human Orotidine-5'-Decarboxylase Domain of Human Uridine Monophosphate Synthetase (Umps) To be Published, |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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