2JFG

Crystal structure of MurD ligase in complex with UMA and ADP

Summary for 2JFG

Entry DOI	10.2210/pdb2jfg/pdb
Related	1E0D 1EEH 1UAG 2JFF 2JFH 2UAG 3UAG 4UAG
Descriptor	UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE, URIDINE-5'-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywords	nucleotide-binding, peptidoglycan synthesis, murd ligase, atp-binding, cell division, uma, adp, ligase, cell wall, cell shape, cell cycle
Biological source	ESCHERICHIA COLI
Total number of polymer chains	1
Total formula weight	49253.16
Authors	Kotnik, M.,Humljan, J.,Contreras-Martel, C.,Oblak, M.,Kristan, K.,Herve, M.,Blanot, D.,Urleb, U.,Gobec, S.,Dessen, A.,Solmajer, T. (deposition date: 2007-02-01, release date: 2007-05-15, Last modification date: 2023-12-13)
Primary citation	Kotnik, M.,Humljan, J.,Contreras-Martel, C.,Oblak, M.,Kristan, K.,Herve, M.,Blanot, D.,Urleb, U.,Gobec, S.,Dessen, A.,Solmajer, T. Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase. J. Mol. Biol., 370:107-115, 2007 Cited by PubMed: 17507028 DOI: 10.1016/j.jmb.2007.04.048 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.52 Å)

Structure validation