2JD0

X-ray structure of mutant 1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXR, Rv2870c, from Mycobacterium tuberculosis, in complex with NADPH

2JD0 の概要

• エントリーDOI: 10.2210/pdb2jd0/pdb
• 関連するPDBエントリー: 2C82 2JCV 2JCX 2JCY 2JCZ 2JD1 2JD2
• 分子名称: 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: oxidoreductase, doxp/mep pathway, isoprene biosynthesis, 1-deoxy-d-xylulose 5-phosphate reductoisomerase, nadp, rv2870c, metal-binding
• 由来する生物種: MYCOBACTERIUM TUBERCULOSIS
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 84431.61

構造登録者

Henriksson, L.M.,Unge, T.,Jones, T.A.,Mowbray, S.L. (登録日: 2007-01-04, 公開日: 2007-05-08, 最終更新日: 2023-12-13)

• 主引用文献: Henriksson, L.M.,Unge, T.,Carlsson, J.,Aqvist, J.,Mowbray, S.L.,Jones, T.A.; Structures of Mycobacterium Tuberculosis 1-Deoxy-D- Xylulose-5-Phosphate Reductoisomerase Provide New Insights Into Catalysis.; J.Biol.Chem., 282:19905-, 2007; PubMed: 17491006; DOI: 10.1074/JBC.M701935200

実験手法

X-RAY DIFFRACTION (2.3 Å)