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2JCN

The crystal structure of BAK1 - a mitochondrial apoptosis regulator

Summary for 2JCN
Entry DOI10.2210/pdb2jcn/pdb
Related1BXL
DescriptorBCL-2 HOMOLOGOUS ANTAGONIST/KILLER, SULFATE ION (3 entities in total)
Functional Keywordsapoptosis, mitochondrial outer membrane permeabilization, oligomerization, cytochrome c release, membrane, transmembrane
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total formula weight19420.76
Authors
Primary citationMoche, M.,Stenmark, P.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Johansson, I.,Karlberg, T.,Kosinska, U.,Kotenyova, T.,Lundgren, S.,Nilsson, M.E.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Upsten, M.,Thorsell, A.G.,Van Den Berg, S.,Weigelt, J.,Nordlund, P.
The Crystal Structure of Bak1 - an Apoptosis Trigger in the Mitochondrial Outer Membrane
To be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

237735

数据于2025-06-18公开中

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