2JCC

AH3 recognition of mutant HLA-A2 W167A

2JCC の概要

• エントリーDOI: 10.2210/pdb2jcc/pdb
• 分子名称: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN, P1049, ... (6 entities in total)
• 機能のキーワード: glycoprotein, immune system, transmembrane, immunoglobulin domain, host-virus interaction, mhc i, membrane, receptor, polymorphism, pyrrolidone carboxylic acid, imunoregulatory complex, class i mhc-tcr co-crystal, ubl conjugation, immune response, hypothetical protein
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 186429.79

構造登録者

Miller, P.,Benhar, Y.P.,Biddison, W.,Collins, E.J. (登録日: 2006-12-21, 公開日: 2007-10-09, 最終更新日: 2023-12-13)

• 主引用文献: Miller, P.,Pazy, Y.,Conti, B.,Riddle, D.,Appella, E.,Collins, E.J.; Single Mhc Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding.; J.Mol.Biol., 373:315-, 2007; PubMed: 17825839; DOI: 10.1016/J.JMB.2007.07.028

実験手法

X-RAY DIFFRACTION (2.5 Å)