2JAP
Clavulanic Acid Dehydrogenase: Structural and Biochemical Analysis of the Final Step in the Biosynthesis of the beta-Lactamase Inhibitor Clavulanic acid
Summary for 2JAP
Entry DOI | 10.2210/pdb2jap/pdb |
Related | 2JAH |
Descriptor | CLAVALDEHYDE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-OXO-4-OXA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, ... (4 entities in total) |
Functional Keywords | short-chain dehydrogenase/reductase, oxidoreductase, antibiotic biosynthesis, beta-lactamase inhibitor |
Biological source | STREPTOMYCES CLAVULIGERUS |
Total number of polymer chains | 4 |
Total formula weight | 109206.70 |
Authors | MacKenzie, A.K.,Kershaw, N.J.,Hernandez, H.,Robinson, C.V.,Schofield, C.J.,Andersson, I. (deposition date: 2006-11-29, release date: 2007-02-20, Last modification date: 2024-05-08) |
Primary citation | Mackenzie, A.K.,Kershaw, N.J.,Hernandez, H.,Robinson, C.V.,Schofield, C.J.,Andersson, I. Clavulanic Acid Dehydrogenase: Structural and Biochemical Analysis of the Final Step in the Biosynthesis of the Beta-Lactamase Inhibitor Clavulanic Acid Biochemistry, 46:1523-, 2007 Cited by PubMed: 17279617DOI: 10.1021/BI061978X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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