2J9J

Atomic-resolution Crystal Structure of Chemically-Synthesized HIV-1 Protease Complexed with Inhibitor JG-365

2J9J の概要

• エントリーDOI: 10.2210/pdb2j9j/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000228
• 分子名称: PROTEASE, INHIBITOR MOLECULE JG365, SULFATE ION, ... (7 entities in total)
• 機能のキーワード: hydrolase-hydrolase inhibitor complex, protease, hydrolase, high resolution, rna-directed dna polymerase, aspartyl protease, human immunodeficiency virus 1, hydrolase- hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: HUMAN IMMUNODEFICIENCY VIRUS 1; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 22855.72

構造登録者

Malito, E.,Shen, Y.,Johnson, E.C.B.,Tang, W.J. (登録日: 2006-11-11, 公開日: 2007-08-28, 最終更新日: 2023-12-13)

• 主引用文献: Johnson, E.C.B.,Malito, E.,Shen, Y.,Pentelute, B.,Rich, D.,Florian, J.,Tang, W.J.,Kent, S.B.H.; Insights from Atomic-Resolution X-Ray Structures of Chemically Synthesized HIV-1 Protease in Complex with Inhibitors.; J.Mol.Biol., 373:573-, 2007; PubMed: 17869270; DOI: 10.1016/J.JMB.2007.07.054

実験手法

X-RAY DIFFRACTION (1.04 Å)