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2J91

Crystal structure of Human Adenylosuccinate Lyase in complex with AMP

Replaces:  2J84
Summary for 2J91
Entry DOI10.2210/pdb2j91/pdb
Related2J84
DescriptorADENYLOSUCCINATE LYASE, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsdisease mutation, adenylosuccinase, succino amp-lyase, purine biosynthesis, adenylosuccinate lyase, adenylosuccinase deficiency, amp, adsl, lyase, saicar, purine, s-amp, epilepsy
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains4
Total formula weight230781.37
Authors
Primary citationStenmark, P.,Moche, M.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Hogbom, M.,Johansson, I.,Karlberg, T.,Kosinska, U.,Kotenyova, T.,Magnusdottir, A.,Nilsson, M.E.,Nilsson-Ehle, P.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Uppsten, M.,Thorsell, A.G.,Van Den Berg, S.,Wallden, K.,Weigelt, J.,Nordlund, P.
Crystal Structure of Human Adenylosuccinate Lyase
To be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

數據於2024-03-27公開中

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