2J91

Crystal structure of Human Adenylosuccinate Lyase in complex with AMP

Replaces:  2J84

Summary for 2J91

• Entry DOI: 10.2210/pdb2j91/pdb
• Related: 2J84
• Descriptor: ADENYLOSUCCINATE LYASE, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: disease mutation, adenylosuccinase, succino amp-lyase, purine biosynthesis, adenylosuccinate lyase, adenylosuccinase deficiency, amp, adsl, lyase, saicar, purine, s-amp, epilepsy
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 4
• Total formula weight: 230781.37

Authors

Stenmark, P.,Moche, M.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Hogbom, M.,Johansson, I.,Karlberg, T.,Kosinska, U.,Kotenyova, T.,Magnusdottir, A.,Nilsson, M.E.,Nilsson-Ehle, P.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Uppsten, M.,Thorsell, A.G.,van Den Berg, S.,Wallden, K.,Weigelt, J.,Nordlund, P. (deposition date: 2006-11-01, release date: 2006-11-07, Last modification date: 2023-12-13)

• Primary citation: Stenmark, P.,Moche, M.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Hogbom, M.,Johansson, I.,Karlberg, T.,Kosinska, U.,Kotenyova, T.,Magnusdottir, A.,Nilsson, M.E.,Nilsson-Ehle, P.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Sundstrom, M.,Uppenberg, J.,Uppsten, M.,Thorsell, A.G.,Van Den Berg, S.,Wallden, K.,Weigelt, J.,Nordlund, P.; Crystal Structure of Human Adenylosuccinate Lyase; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)