2J83

Ulilysin metalloprotease in complex with batimastat.

Summary for 2J83

• Entry DOI: 10.2210/pdb2j83/pdb
• Related: 2CKI
• Descriptor: ULILYSIN, 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: hydrolase, igfbp protease, metalloprotease, hydroxamate inhibitor, cancer, metzincin
• Biological source: METHANOSARCINA ACETIVORANS
• Total number of polymer chains: 2
• Total formula weight: 59811.24

Authors

Garcia-Castellanos, R.,Tallant, C.,Marrero, A.,Sola, M.,Baumann, U.,Gomis-Ruth, F.X. (deposition date: 2006-10-18, release date: 2006-12-19, Last modification date: 2023-12-13)

• Primary citation: Garcia-Castellanos, R.,Tallant, C.,Marrero, A.,Sola, M.,Baumann, U.,Gomis-Ruth, F.X.; Substrate Specificity of a Metalloprotease of the Pappalysin Family Revealed by an Inhibitor and a Product Complex.; Arch.Biochem.Biophys., 457:57-, 2007; PubMed: 17097044; DOI: 10.1016/J.ABB.2006.10.004

Experimental method

X-RAY DIFFRACTION (2 Å)