2J83
Ulilysin metalloprotease in complex with batimastat.
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 997 |
| Chain | Residue |
| A | TRP240 |
| A | GLU243 |
| A | PRO249 |
| A | GLN262 |
| A | ALA263 |
| A | HOH2169 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 998 |
| Chain | Residue |
| A | HOH2149 |
| A | HOH2154 |
| A | HOH2164 |
| A | HOH2165 |
| A | ASP254 |
| A | VAL256 |
| A | THR259 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 999 |
| Chain | Residue |
| A | HIS228 |
| A | HIS232 |
| A | HIS238 |
| A | BAT996 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 997 |
| Chain | Residue |
| B | TRP240 |
| B | GLU243 |
| B | PRO249 |
| B | GLN262 |
| B | ALA263 |
| B | HOH2168 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 998 |
| Chain | Residue |
| B | ASP254 |
| B | VAL256 |
| B | THR259 |
| B | HOH2172 |
| B | HOH2173 |
| B | HOH2184 |
| B | HOH2185 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 999 |
| Chain | Residue |
| B | HIS228 |
| B | HIS232 |
| B | HIS238 |
| B | BAT996 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 2326 |
| Chain | Residue |
| A | ASP152 |
| A | HOH2075 |
| A | HOH2119 |
| B | ASP152 |
| B | HOH2092 |
| B | HOH2141 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE BAT A 996 |
| Chain | Residue |
| A | ASP186 |
| A | ILE187 |
| A | LEU188 |
| A | GLY189 |
| A | HIS228 |
| A | GLU229 |
| A | HIS232 |
| A | HIS238 |
| A | TYR292 |
| A | ZN999 |
| A | HOH2220 |
| B | LEU244 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE BAT B 996 |
| Chain | Residue |
| A | LEU244 |
| B | ASP186 |
| B | ILE187 |
| B | LEU188 |
| B | GLY189 |
| B | HIS228 |
| B | GLU229 |
| B | HIS232 |
| B | HIS238 |
| B | TYR292 |
| B | ZN999 |
| B | HOH2242 |
| B | HOH2243 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1327 |
| Chain | Residue |
| A | GLU63 |
| A | VAL65 |
| A | GLY120 |
| A | ASN310 |
| A | ASP314 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1328 |
| Chain | Residue |
| A | PRO68 |
| A | THR127 |
| A | LYS128 |
| A | ARG169 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 1326 |
| Chain | Residue |
| B | ALA126 |
| B | THR127 |
| B | LYS128 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1327 |
| Chain | Residue |
| B | GLU63 |
| B | VAL65 |
| B | LEU119 |
| B | GLY120 |
| B | ASN310 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TATHEIGHWL |
| Chain | Residue | Details |
| A | THR225-LEU234 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"16627477","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17097044","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16627477","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16627477","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17097044","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16627477","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17097044","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
