2J7U

Dengue virus NS5 RNA dependent RNA polymerase domain

Summary for 2J7U

• Entry DOI: 10.2210/pdb2j7u/pdb
• Related: 2J7W
• Descriptor: RNA DEPENDENT RNA POLYMERASE, ZINC ION, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: nucleoside binding site, flavivirus, high-throughput assay, viral protein
• Biological source: DENGUE VIRUS
• Cellular location: Envelope protein E: Virion membrane; Multi- pass membrane protein: Q6DLV0
• Total number of polymer chains: 1
• Total formula weight: 73937.56

Authors

Yap, T.L.,Xu, T.,Chen, Y.L.,Malet, H.,Egloff, M.P.,Canard, B.,Vasudevan, S.G.,Lescar, J. (deposition date: 2006-10-17, release date: 2007-03-13, Last modification date: 2023-12-13)

• Primary citation: Yap, T.L.,Xu, T.,Chen, Y.L.,Malet, H.,Egloff, M.P.,Canard, B.,Vasudevan, S.G.,Lescar, J.; Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.; J.Virol., 81:4753-, 2007; PubMed: 17301146; DOI: 10.1128/JVI.02283-06

Experimental method

X-RAY DIFFRACTION (1.85 Å)