2J0L
Crystal structure of a the active conformation of the kinase domain of focal adhesion kinase with a phosphorylated activation loop.
Summary for 2J0L
Entry DOI | 10.2210/pdb2j0l/pdb |
Related | 1KTM 1PV3 1QVX 2AEH 2AL6 2J0J 2J0K 2J0M |
Descriptor | FOCAL ADHESION KINASE 1, SULFATE ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | focal adhesion, cell migration, phosphorylation, ferm, kinase, transferase, atp-binding, integrin signaling, nucleotide-binding, tyrosine-protein kinase |
Biological source | GALLUS GALLUS (CHICKEN) |
Total number of polymer chains | 1 |
Total formula weight | 32547.32 |
Authors | Lietha, D.,Cai, X.,Li, Y.,Schaller, M.D.,Eck, M.J. (deposition date: 2006-08-03, release date: 2007-06-26, Last modification date: 2023-12-13) |
Primary citation | Lietha, D.,Cai, X.,Ceccarelli, D.F.J.,Li, Y.,Schaller, M.D.,Eck, M.J. Structural Basis for the Autoinhibition of Focal Adhesion Kinase Cell(Cambridge,Mass.), 129:1177-, 2007 Cited by PubMed: 17574028DOI: 10.1016/J.CELL.2007.05.041 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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