2J0L

Crystal structure of a the active conformation of the kinase domain of focal adhesion kinase with a phosphorylated activation loop.

Summary for 2J0L

Entry DOI	10.2210/pdb2j0l/pdb
Related	1KTM 1PV3 1QVX 2AEH 2AL6 2J0J 2J0K 2J0M
Descriptor	FOCAL ADHESION KINASE 1, SULFATE ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	focal adhesion, cell migration, phosphorylation, ferm, kinase, transferase, atp-binding, integrin signaling, nucleotide-binding, tyrosine-protein kinase
Biological source	GALLUS GALLUS (CHICKEN)
Total number of polymer chains	1
Total formula weight	32547.32
Authors	Lietha, D.,Cai, X.,Li, Y.,Schaller, M.D.,Eck, M.J. (deposition date: 2006-08-03, release date: 2007-06-26, Last modification date: 2023-12-13)
Primary citation	Lietha, D.,Cai, X.,Ceccarelli, D.F.J.,Li, Y.,Schaller, M.D.,Eck, M.J. Structural Basis for the Autoinhibition of Focal Adhesion Kinase Cell(Cambridge,Mass.), 129:1177-, 2007 Cited by PubMed: 17574028 DOI: 10.1016/J.CELL.2007.05.041 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation