2IU0

crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase

「2B0W」から置き換えられました

2IU0 の概要

• エントリーDOI: 10.2210/pdb2iu0/pdb
• 分子名称: BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, POTASSIUM ION, 1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE 2,2-DIOXIDE, ... (4 entities in total)
• 機能のキーワード: multifunctional enzyme, transition state analogue, atic, impch, hydrolase, inhibitor, transferase, structure-base, purine biosynthesis
• 由来する生物種: GALLUS GALLUS (CHICKEN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 129261.77

構造登録者

Xu, L.,Chong, Y.,Hwang, I.,Onofrio, A.D.,Amore, K.,Beardsley, G.P.,Li, C.,Olson, A.J.,Boger, D.L.,Wilson, I.A. (登録日: 2006-05-26, 公開日: 2007-02-20, 最終更新日: 2023-12-13)

• 主引用文献: Xu, L.,Chong, Y.,Hwang, I.,D'Onofrio, A.,Amore, K.,Beardsley, G.P.,Li, C.,Olson, A.J.,Boger, D.L.,Wilson, I.A.; Structure-Based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase; J.Biol.Chem., 282:13033-, 2007; PubMed: 17324932; DOI: 10.1074/JBC.M607293200

実験手法

X-RAY DIFFRACTION (2.53 Å)