2IRF

CRYSTAL STRUCTURE OF AN IRF-2/DNA COMPLEX.

Summary for 2IRF

• Entry DOI: 10.2210/pdb2irf/pdb
• Descriptor: DNA (5'-D(P*AP*AP*GP*TP*GP*AP*AP*AP*GP*(5IU)P*GP*A)-3'), DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P*T)-3'), INTERFERON REGULATORY FACTOR 2, ... (5 entities in total)
• Functional Keywords: transcription factor, ifn induction, irf family, gene regulation-dna complex, gene regulation/dna
• Biological source: Mus musculus (house mouse)
• Cellular location: Nucleus: P23906
• Total number of polymer chains: 12
• Total formula weight: 104701.14

Authors

Fujii, Y.,Shimizu, T.,Kusumoto, M.,Kyogoku, Y.,Taniguchi, T.,Hakoshima, T. (deposition date: 1999-05-30, release date: 1999-10-08, Last modification date: 2023-12-27)

• Primary citation: Fujii, Y.,Shimizu, T.,Kusumoto, M.,Kyogoku, Y.,Taniguchi, T.,Hakoshima, T.; Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences.; EMBO J., 18:5028-5041, 1999; PubMed: 10487755; DOI: 10.1093/emboj/18.18.5028

Experimental method

X-RAY DIFFRACTION (2.2 Å)