2IRF
CRYSTAL STRUCTURE OF AN IRF-2/DNA COMPLEX.
Summary for 2IRF
Entry DOI | 10.2210/pdb2irf/pdb |
Descriptor | DNA (5'-D(P*AP*AP*GP*TP*GP*AP*AP*AP*GP*(5IU)P*GP*A)-3'), DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P*T)-3'), INTERFERON REGULATORY FACTOR 2, ... (5 entities in total) |
Functional Keywords | transcription factor, ifn induction, irf family, gene regulation-dna complex, gene regulation/dna |
Biological source | Mus musculus (house mouse) |
Cellular location | Nucleus: P23906 |
Total number of polymer chains | 12 |
Total formula weight | 104701.14 |
Authors | Fujii, Y.,Shimizu, T.,Kusumoto, M.,Kyogoku, Y.,Taniguchi, T.,Hakoshima, T. (deposition date: 1999-05-30, release date: 1999-10-08, Last modification date: 2023-12-27) |
Primary citation | Fujii, Y.,Shimizu, T.,Kusumoto, M.,Kyogoku, Y.,Taniguchi, T.,Hakoshima, T. Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. EMBO J., 18:5028-5041, 1999 Cited by PubMed: 10487755DOI: 10.1093/emboj/18.18.5028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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