2IQD
Crystal Structure of Aldose Reductase complexed with Lipoic Acid
Summary for 2IQD
| Entry DOI | 10.2210/pdb2iqd/pdb |
| Related | 2INE 2INZ 2IPW 2IQ0 2IS7 |
| Descriptor | Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, LIPOIC ACID, ... (4 entities in total) |
| Functional Keywords | tim-barrel, ari, aldo-keto reductase, lipoic, oxidoreductase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P15121 |
| Total number of polymer chains | 1 |
| Total formula weight | 36716.88 |
| Authors | Harrison, D.H.T.,Carlson, E.,Pape, E.,Brownlee, J.M. (deposition date: 2006-10-13, release date: 2006-11-28, Last modification date: 2023-08-30) |
| Primary citation | Brownlee, J.M.,Carlson, E.,Milne, A.C.,Pape, E.,Harrison, D.H.T. Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes. Bioorg.Chem., 34:424-444, 2006 Cited by PubMed: 17083960DOI: 10.1016/j.bioorg.2006.09.004 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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