2IPI

Crystal Structure of Aclacinomycin Oxidoreductase

2IPI の概要

• エントリーDOI: 10.2210/pdb2ipi/pdb
• 分子名称: Aclacinomycin oxidoreductase (AknOx), METHYL (2S,4R)-2-ETHYL-2,5,7-TRIHYDROXY-6,11-DIOXO-4-{[2,3,6-TRIDEOXY-4-O-{2,6-DIDEOXY-4-O-[(2S,6S)-6-METHYL-5-OXOTETRAHYDRO-2H-PYRAN-2-YL]-ALPHA-D-LYXO-HEXOPYRANOSYL}-3-(DIMETHYLAMINO)-D-RIBO-HEXOPYRANOSYL]OXY}-1,2,3,4,6,11-HEXAHYDROTETRACENE-1-CARBOXYLATE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: anthracycline, aclacinomycin, oxidoreductase, flavoenzyme, twinning, mad
• 由来する生物種: Streptomyces galilaeus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 232841.08

構造登録者

Sultana, A.,Kursula, I.,Schneider, G.,Alexeev, I.,Niemi, J.,Mantsala, P. (登録日: 2006-10-12, 公開日: 2007-01-23, 最終更新日: 2011-07-13)

• 主引用文献: Sultana, A.,Alexeev, I.,Kursula, I.,Mantsala, P.,Niemi, J.,Schneider, G.; Structure determination by multiwavelength anomalous diffraction of aclacinomycin oxidoreductase: indications of multidomain pseudomerohedral twinning.; Acta Crystallogr.,Sect.D, 63:149-159, 2007; PubMed: 17242508; DOI: 10.1107/S0907444906044271

実験手法

X-RAY DIFFRACTION (1.65 Å)