2IOC

The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partenring

Summary for 2IOC

Entry DOI	10.2210/pdb2ioc/pdb
Descriptor	Three prime repair exonuclease 1, MANGANESE (II) ION, 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, ... (4 entities in total)
Functional Keywords	proline helix, nucleotide complex, dnaq family, hydrolase
Biological source	Mus musculus (house mouse)
Cellular location	Nucleus: Q91XB0
Total number of polymer chains	2
Total formula weight	53717.70
Authors	de Silva, U.,Hollis, T. (deposition date: 2006-10-10, release date: 2007-02-20, Last modification date: 2018-02-14)
Primary citation	de Silva, U.,Choudhury, S.,Bailey, S.L.,Harvey, S.,Perrino, F.W.,Hollis, T. The Crystal Structure of TREX1 Explains the 3' Nucleotide Specificity and Reveals a Polyproline II Helix for Protein Partnering. J.Biol.Chem., 282:10537-10543, 2007 Cited by PubMed: 17293595 DOI: 10.1074/jbc.M700039200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation