2ILV

crystal structure of multifunctional sialyltransferase from Pasteurella multocida with CMP and alpha-lactose bound

Summary for 2ILV

• Entry DOI: 10.2210/pdb2ilv/pdb
• Related: 2IHZ
• Related PRD ID: PRD_900008
• Descriptor: Alpha-2,3/2,6-sialyltransferase/sialidase, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, CYTIDINE-5'-MONOPHOSPHATE, ... (4 entities in total)
• Functional Keywords: sialyltransferase, cmp, alpha-lactose, two rossmann domains, transferase
• Biological source: Pasteurella multocida
• Total number of polymer chains: 1
• Total formula weight: 47264.15

Authors

Fisher, A.J.,Ni, L. (deposition date: 2006-10-03, release date: 2007-05-22, Last modification date: 2023-08-30)

• Primary citation: Ni, L.,Chokhawala, H.A.,Cao, H.,Henning, R.,Ng, L.,Huang, S.,Yu, H.,Chen, X.,Fisher, A.J.; Crystal Structures of Pasteurella multocida Sialyltransferase Complexes with Acceptor and Donor Analogues Reveal Substrate Binding Sites and Catalytic Mechanism.; Biochemistry, 46:6288-6298, 2007; PubMed: 17487984; DOI: 10.1021/bi700346w

Experimental method

X-RAY DIFFRACTION (2.27 Å)