2IJM

Crystal Structure of Focal Adhesion Kinase Domain with 2 molecules in the Asymmetric Unit Complexed with ADP and ATP

Summary for 2IJM

• Entry DOI: 10.2210/pdb2ijm/pdb
• Descriptor: Focal Adhesion Kinase 1, ADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: kinase catalytic domain, signaling protein, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cell junction, focal adhesion: Q05397
• Total number of polymer chains: 2
• Total formula weight: 65396.72

Authors

Lee, C.C. (deposition date: 2006-09-29, release date: 2007-08-14, Last modification date: 2024-10-30)

• Primary citation: Andersen, C.B.,Ng, K.,Ficarro, S.,Vu, C.,Choi, H.-S.,He, Y.,Spraggon, G.,Gray, N.,Lee, C.C.; Crystal Structure of Focal Adhesion Kinase Catalytic Domain Complexed with ATP and Novel 7H-Pyrrolo [2,3-d] pyrimidine Inhibitor Scaffolds; To be Published,

Experimental method

X-RAY DIFFRACTION (2.187 Å)