2IJM

Crystal Structure of Focal Adhesion Kinase Domain with 2 molecules in the Asymmetric Unit Complexed with ADP and ATP

2IJM の概要

• エントリーDOI: 10.2210/pdb2ijm/pdb
• 分子名称: Focal Adhesion Kinase 1, ADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: kinase catalytic domain, signaling protein, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell junction, focal adhesion: Q05397
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65396.72

構造登録者

Lee, C.C. (登録日: 2006-09-29, 公開日: 2007-08-14, 最終更新日: 2023-08-30)

• 主引用文献: Andersen, C.B.,Ng, K.,Ficarro, S.,Vu, C.,Choi, H.-S.,He, Y.,Spraggon, G.,Gray, N.,Lee, C.C.; Crystal Structure of Focal Adhesion Kinase Catalytic Domain Complexed with ATP and Novel 7H-Pyrrolo [2,3-d] pyrimidine Inhibitor Scaffolds; To be Published,

実験手法

X-RAY DIFFRACTION (2.187 Å)