2IJD
Crystal Structure of the Poliovirus Precursor Protein 3CD
Summary for 2IJD
Entry DOI | 10.2210/pdb2ijd/pdb |
Descriptor | Picornain 3C, RNA-directed RNA polymerase, ZINC ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | rna polymerase, rna-dependent rna polymerase, poliovirus, picornavirus, protease, hydrolase, transferase |
Biological source | Human poliovirus 1 |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300 |
Total number of polymer chains | 2 |
Total formula weight | 144917.53 |
Authors | Marcotte, L.L.,Gohara, D.W.,Filman, D.J.,Hogle, J.M. (deposition date: 2006-09-29, release date: 2007-02-13, Last modification date: 2023-08-30) |
Primary citation | Marcotte, L.L.,Wass, A.B.,Gohara, D.W.,Pathak, H.B.,Arnold, J.J.,Filman, D.J.,Cameron, C.E.,Hogle, J.M. Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase. J.Virol., 81:3583-3596, 2007 Cited by PubMed: 17251299DOI: 10.1128/JVI.02306-06 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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