2IJ5
Crystal structure of cytochrome P450 CYP121, P212121 space group
Summary for 2IJ5
Entry DOI | 10.2210/pdb2ij5/pdb |
Related | 1N40 2IJ7 |
Descriptor | Cytochrome P450 121, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total) |
Functional Keywords | tuberculosis, cyp121, cytochrome p450, azole ligation, fluconazole, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Cellular location | Cytoplasm (By similarity): P0A514 |
Total number of polymer chains | 6 |
Total formula weight | 264110.48 |
Authors | Roujeinikova, A.,Leys, D. (deposition date: 2006-09-29, release date: 2006-11-07, Last modification date: 2023-08-30) |
Primary citation | Seward, H.E.,Roujeinikova, A.,McLean, K.J.,Munro, A.W.,Leys, D. Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode. J.Biol.Chem., 281:39437-39443, 2006 Cited by PubMed: 17028183DOI: 10.1074/jbc.M607665200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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