2IJ0

Structural basis of T cell specificity and activation by the bacterial superantigen toxic shock syndrome toxin-1

Summary for 2IJ0

Entry DOI	10.2210/pdb2ij0/pdb
Descriptor	Toxic shock syndrome toxin-1, penultimate affinity-matured variant of hVbeta 2.1, D10 (3 entities in total)
Functional Keywords	superantigen, protein-protein interaction, protein binding
Biological source	Staphylococcus aureus More
Total number of polymer chains	4
Total formula weight	69808.48
Authors	Moza, B.,Varma, A.K.,Buonpane, R.A.,Zhu, P.,Herfst, C.A.,Nicholson, M.J.,Wilbuer, A.K.,Nulifer, S.,Wucherpfenning, K.W.,McCormick, J.K.,Kranz, D.M.,Sundberg, E.J. (deposition date: 2006-09-28, release date: 2007-02-20, Last modification date: 2011-07-13)
Primary citation	Moza, B.,Varma, A.K.,Buonpane, R.A.,Zhu, P.,Herfst, C.A.,Nicholson, M.J.,Wilbuer, A.K.,Seth, N.P.,Wucherpfennig, K.W.,McCormick, J.K.,Kranz, D.M.,Sundberg, E.J. Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1. Embo J., 26:1187-1197, 2007 Cited by PubMed: 17268555 DOI: 10.1038/sj.emboj.7601531 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation