2IIM
SH3 Domain of Human Lck
Summary for 2IIM
Entry DOI | 10.2210/pdb2iim/pdb |
Related | 1LCK |
Descriptor | Proto-oncogene tyrosine-protein kinase LCK, ZINC ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | beta-barrels, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P06239 |
Total number of polymer chains | 1 |
Total formula weight | 7194.29 |
Authors | Romir, J.,Egerer-Sieber, C.,Muller, Y.A. (deposition date: 2006-09-28, release date: 2006-11-07, Last modification date: 2023-08-30) |
Primary citation | Romir, J.,Lilie, H.,Egerer-Sieber, C.,Bauer, F.,Sticht, H.,Muller, Y.A. Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs. J.Mol.Biol., 365:1417-1428, 2007 Cited by PubMed: 17118402DOI: 10.1016/j.jmb.2006.10.058 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1 Å) |
Structure validation
Download full validation report