2IGO

Crystal structure of pyranose 2-oxidase H167A mutant with 2-fluoro-2-deoxy-D-glucose

Summary for 2IGO

Entry DOI	10.2210/pdb2igo/pdb
Related	1TT0 2IGK 2IGM 2IGN
Descriptor	Pyranose oxidase, 2-deoxy-2-fluoro-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	oxidoreductase, gmc oxidoreductase, h167a mutant, 2-fluoro-2-deoxy-d-glucose, rossmann fold, phbh fold, homotetramer, 8-alpha-(n3) histidyl flavinylation
Biological source	Trametes ochracea
Total number of polymer chains	8
Total formula weight	562515.26
Authors	Divne, C. (deposition date: 2006-09-22, release date: 2006-10-10, Last modification date: 2024-02-21)
Primary citation	Kujawa, M.,Ebner, H.,Leitner, C.,Hallberg, B.M.,Prongjit, M.,Sucharitakul, J.,Ludwig, R.,Rudsander, U.,Peterbauer, C.,Chaiyen, P.,Haltrich, D.,Divne, C. Structural basis for substrate binding and regioselective oxidation of monosaccharides at c3 by pyranose 2-oxidase. J.Biol.Chem., 281:35104-35115, 2006 Cited by PubMed: 16984920 DOI: 10.1074/jbc.M604718200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation