2IFG

Structure of the extracellular segment of human TRKA in complex with nerve growth factor

2IFG の概要

• エントリーDOI: 10.2210/pdb2ifg/pdb
• 分子名称: High affinity nerve growth factor receptor, Beta-nerve growth factor, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: trk, trka, ngf, nerve growth factor, receptor-ligand complex, transferase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 109542.64

構造登録者

He, X.,Garcia, K.C. (登録日: 2006-09-20, 公開日: 2007-02-13, 最終更新日: 2023-08-30)

• 主引用文献: Wehrman, T.,He, X.,Raab, B.,Dukipatti, A.,Blau, H.,Garcia, K.C.; Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors.; Neuron, 53:25-38, 2007; PubMed: 17196528; DOI: 10.1016/j.neuron.2006.09.034

実験手法

X-RAY DIFFRACTION (3.4 Å)