2IED

CRYSTAL STRUCTURE of ISONIAZID-RESISTANT S94A ENOYL-ACP(COA) REDUCTASE MUTANT ENZYME FROM MYCOBACTERIUM TUBERCULOSIS UNCOMPLEXED

Summary for 2IED

• Entry DOI: 10.2210/pdb2ied/pdb
• Related: 2IDZ 2IE0 2IEB
• Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADH] (2 entities in total)
• Functional Keywords: enoyl-acyl carrier protein, inha reductase, oxidoreductase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 4
• Total formula weight: 113630.34

Authors

Dias, M.V.B.,Prado, A.M.X.,Vasconcelos, I.B.,Fadel, V.,Basso, L.A.,Santos, D.S.,Azevedo Jr., W.F. (deposition date: 2006-09-18, release date: 2007-07-24, Last modification date: 2023-08-30)

• Primary citation: Dias, M.V.,Vasconcelos, I.B.,Prado, A.M.,Fadel, V.,Basso, L.A.,de Azevedo, W.F.,Santos, D.S.; Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis.; J.Struct.Biol., 159:369-380, 2007; PubMed: 17588773; DOI: 10.1016/j.jsb.2007.04.009

Experimental method

X-RAY DIFFRACTION (2.14 Å)