2IED

CRYSTAL STRUCTURE of ISONIAZID-RESISTANT S94A ENOYL-ACP(COA) REDUCTASE MUTANT ENZYME FROM MYCOBACTERIUM TUBERCULOSIS UNCOMPLEXED

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Enoyl-[acyl-carrier-protein] reductase [NADH]	polymer	268	28407.6	4	UniProt (P0A5Y6) Pfam (PF13561) UniProt (by SIFTS) (P9WGR1)	Mycobacterium tuberculosis	NADH-dependent enoyl-ACP reductase
2	E, F, G, H (A, B, C, D)	water	water		18.0	701	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 269 (UniProt: P0A5Y6)

PDB	External Database	Details
Ala 94	Ser 94	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	113630.3
All*	Total formula weight	113630.3

*Water molecules are not included.