2IE1

Polyamines stabilize left-handed Z-DNA. We found new type of polyamine which stabilize left-handed Z-DNA by X-ray crystallography

Summary for 2IE1

• Entry DOI: 10.2210/pdb2ie1/pdb
• Related: 1dj6 1pe6 1pip 292d 293d 2DY6 2HYH 336d
• Descriptor: DNA (5'-D(*DCP*DGP*DCP*DGP*DCP*DG)-3'), N-(2-AMINOETHYL)-N'-{2-[(2-AMINOETHYL)AMINO]ETHYL}ETHANE-1,2-DIAMINE (3 entities in total)
• Functional Keywords: deoxy nucleic acid, d(cgcgcg)2, z-dna, n1-{2-[2-(2-amino-ethylamino)-ethylamino]-ethyl}-ethane-1, 2-diamine, pa(2222), polyamine, metal free crystal structure, dna
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 3999.01

Authors

Ohishi, H.,Odoko, M.,Tsukamoto, K.,Hiyama, Y.,Maezaki, N.,Grzeskowiak, K.,Ishida, T.,Tanaka, T.,Okabe, N.,Fukuyama, K. (deposition date: 2006-09-16, release date: 2007-10-09, Last modification date: 2023-11-29)

• Primary citation: Ohishi, H.,Odoko, M.,Tsukamoto, K.,Hiyama, Y.,Maezaki, N.,Grzeskowiak, K.,Ishida, T.,Tanaka, T.,Okabe, N.,Fukuyama, K.; Polyamines stabilize left-handed Z-DNA. We found new type of polyamine which stabilize left-handed Z-DNA by X-ray crystallography; To be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)