2I9G
DNA Polymerase Beta with a Benzo[c]phenanthrene diol epoxide adducted guanine base
Summary for 2I9G
Entry DOI | 10.2210/pdb2i9g/pdb |
Descriptor | 5'-D(P*GP*TP*CP*GP*G)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', ... (8 entities in total) |
Functional Keywords | mutagenesis, base excision repair, nucleotidyl transferase, dna adduct, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 48089.07 |
Authors | Batra, V.K.,Wilson, S.H.,Beard, W.A.,Pedersen, L.C. (deposition date: 2006-09-05, release date: 2006-10-24, Last modification date: 2023-08-30) |
Primary citation | Batra, V.K.,Shock, D.D.,Prasad, R.,Beard, W.A.,Hou, E.W.,Pedersen, L.C.,Sayer, J.M.,Yagi, H.,Kumar, S.,Jerina, D.M.,Wilson, S.H. Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features. Proc.Natl.Acad.Sci.Usa, 103:17231-17236, 2006 Cited by PubMed: 17079493DOI: 10.1073/pnas.0605069103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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