2I7C

The crystal structure of spermidine synthase from p. falciparum in complex with AdoDATO

2I7C の概要

• エントリーDOI: 10.2210/pdb2i7c/pdb
• 関連するPDBエントリー: 1JQ3 1ZDZ 2HTE
• 分子名称: Spermidine synthase, S-ADENOSYL-1,8-DIAMINO-3-THIOOCTANE, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ... (5 entities in total)
• 機能のキーワード: transferase, spermidine synthase, structural genomics consortium, sgc
• 由来する生物種: Plasmodium falciparum
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 98714.94

構造登録者

Qiu, W.,Dong, A.,Ren, H.,Wu, H.,Wasney, G.,Vedadi, M.,Lew, J.,Kozieradski, I.,Edwards, A.M.,Arrowsmith, C.H.,Weigelt, J.,Sundstrom, M.,Plotnikov, A.N.,Bochkarev, A.,Hui, R.,Structural Genomics Consortium (SGC) (登録日: 2006-08-30, 公開日: 2006-09-12, 最終更新日: 2023-08-30)

• 主引用文献: Dufe, V.T.,Qiu, W.,Muller, I.B.,Hui, R.,Walter, R.D.,Al-Karadaghi, S.; Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.; J.Mol.Biol., 373:167-177, 2007; PubMed: 17822713; DOI: 10.1016/j.jmb.2007.07.053

実験手法

X-RAY DIFFRACTION (1.71 Å)