2I4T

Crystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with Imm-A

2I4T の概要

• エントリーDOI: 10.2210/pdb2i4t/pdb
• 分子名称: Trichomonas vaginalis purine nucleoside phosphorylase, PHOSPHATE ION, 3,4-PYRROLIDINEDIOL,2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)-2S,3S,4R,5R, ... (4 entities in total)
• 機能のキーワード: purine nucleoside phosphorylase, transferase
• 由来する生物種: Trichomonas vaginalis
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 79126.08

構造登録者

Rinaldo-Matthis, A.,Schramm, V.L.,Almo, S.C. (登録日: 2006-08-22, 公開日: 2007-06-05, 最終更新日: 2024-02-21)

• 主引用文献: Rinaldo-Matthis, A.,Wing, C.,Ghanem, M.,Deng, H.,Wu, P.,Gupta, A.,Tyler, P.C.,Evans, G.B.,Furneaux, R.H.,Almo, S.C.,Wang, C.C.,Schramm, V.L.; Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.; Biochemistry, 46:659-668, 2007; PubMed: 17223688; DOI: 10.1021/bi061515r

実験手法

X-RAY DIFFRACTION (2.74 Å)