2I3A

Crystal structure of N-Acetyl-gamma-Glutamyl-Phosphate Reductase (Rv1652) from Mycobacterium tuberculosis

2I3A の概要

• エントリーDOI: 10.2210/pdb2i3a/pdb
• 分子名称: N-acetyl-gamma-glutamyl-phosphate reductase, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
• 機能のキーワード: dimer interface beta sandwich, tetramer, rossmann fold, structural genomics, mycobacterium tuberculosis structural proteomics project, xmtb, oxidoreductase
• 由来する生物種: Mycobacterium tuberculosis
• 細胞内の位置: Cytoplasm (Probable): P63562
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 146201.66

構造登録者

Cherney, L.T.,Cherney, M.M.,Garen, C.R.,Moraidin, F.,James, M.N.G.,Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) (登録日: 2006-08-17, 公開日: 2006-08-29, 最終更新日: 2024-02-21)

• 主引用文献: Cherney, L.T.,Cherney, M.M.,Garen, C.R.,Niu, C.,Moradian, F.,James, M.N.G.; Crystal Structure of N-acetyl-gamma-glutamyl-phosphate Reductase from Mycobacterium tuberculosis in Complex with NADP(+).; J.Mol.Biol., 367:1357-1369, 2007; PubMed: 17316682; DOI: 10.1016/j.jmb.2007.01.033

実験手法

X-RAY DIFFRACTION (2.15 Å)