2I22
Crystal structure of Escherichia coli phosphoheptose isomerase in complex with reaction substrate sedoheptulose 7-phosphate
Summary for 2I22
| Entry DOI | 10.2210/pdb2i22/pdb |
| Related | 2I2W |
| Descriptor | Phosphoheptose isomerase, D-ALTRO-HEPT-2-ULOSE 7-PHOSPHATE (3 entities in total) |
| Functional Keywords | lipopolysaccharide biosynthesis, phosphoheptose isomerase, isomerase |
| Biological source | Escherichia coli |
| Cellular location | Cytoplasm: P63224 |
| Total number of polymer chains | 4 |
| Total formula weight | 92346.73 |
| Authors | Blakely, K.,Zhang, K.,DeLeon, G.,Wright, G.,Junop, M. (deposition date: 2006-08-15, release date: 2007-08-21, Last modification date: 2023-08-30) |
| Primary citation | Taylor, P.L.,Blakely, K.M.,de Leon, G.P.,Walker, J.R.,McArthur, F.,Evdokimova, E.,Zhang, K.,Valvano, M.A.,Wright, G.D.,Junop, M.S. Structure and Function of Sedoheptulose-7-phosphate Isomerase, a Critical Enzyme for Lipopolysaccharide Biosynthesis and a Target for Antibiotic Adjuvants J.Biol.Chem., 283:2835-2845, 2008 Cited by PubMed: 18056714DOI: 10.1074/jbc.M706163200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report
