2I22

Crystal structure of Escherichia coli phosphoheptose isomerase in complex with reaction substrate sedoheptulose 7-phosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0008270	molecular_function	zinc ion binding
A	0008968	molecular_function	D-sedoheptulose 7-phosphate isomerase activity
A	0009103	biological_process	lipopolysaccharide biosynthetic process
A	0009244	biological_process	lipopolysaccharide core region biosynthetic process
A	0016853	molecular_function	isomerase activity
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0051289	biological_process	protein homotetramerization
A	0097367	molecular_function	carbohydrate derivative binding
A	1901135	biological_process	carbohydrate derivative metabolic process
A	2001061	biological_process	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0008270	molecular_function	zinc ion binding
B	0008968	molecular_function	D-sedoheptulose 7-phosphate isomerase activity
B	0009103	biological_process	lipopolysaccharide biosynthetic process
B	0009244	biological_process	lipopolysaccharide core region biosynthetic process
B	0016853	molecular_function	isomerase activity
B	0032991	cellular_component	protein-containing complex
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0051289	biological_process	protein homotetramerization
B	0097367	molecular_function	carbohydrate derivative binding
B	1901135	biological_process	carbohydrate derivative metabolic process
B	2001061	biological_process	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0008270	molecular_function	zinc ion binding
C	0008968	molecular_function	D-sedoheptulose 7-phosphate isomerase activity
C	0009103	biological_process	lipopolysaccharide biosynthetic process
C	0009244	biological_process	lipopolysaccharide core region biosynthetic process
C	0016853	molecular_function	isomerase activity
C	0032991	cellular_component	protein-containing complex
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	0051289	biological_process	protein homotetramerization
C	0097367	molecular_function	carbohydrate derivative binding
C	1901135	biological_process	carbohydrate derivative metabolic process
C	2001061	biological_process	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005975	biological_process	carbohydrate metabolic process
D	0008270	molecular_function	zinc ion binding
D	0008968	molecular_function	D-sedoheptulose 7-phosphate isomerase activity
D	0009103	biological_process	lipopolysaccharide biosynthetic process
D	0009244	biological_process	lipopolysaccharide core region biosynthetic process
D	0016853	molecular_function	isomerase activity
D	0032991	cellular_component	protein-containing complex
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	0051289	biological_process	protein homotetramerization
D	0097367	molecular_function	carbohydrate derivative binding
D	1901135	biological_process	carbohydrate derivative metabolic process
D	2001061	biological_process	D-glycero-D-manno-heptose 7-phosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE I22 B 900

Chain	Residue
B	GLY54
B	SER55
B	THR120
B	ALA168
B	ASP169
B	GLN172
C	HIS61
C	GLU65
C	HIS180

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	28
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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