2HTW

N4 neuraminidase in complex with DANA

Summary for 2HTW

• Entry DOI: 10.2210/pdb2htw/pdb
• Related: 2HT5 2HT7 2HT8 2HTQ 2HTR 2HTU 2HTV 2HTY 2HU0 2HU4
• Descriptor: Neuraminidase, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID (2 entities in total)
• Functional Keywords: n4, neuraminidase, dana, hydrolase
• Biological source: Influenza A virus
• Total number of polymer chains: 1
• Total formula weight: 43224.25

Authors

Russell, R.J.,Haire, L.F.,Stevens, D.J.,Collins, P.J.,Lin, Y.P.,Blackburn, G.M.,Hay, A.J.,Gamblin, S.J.,Skehel, J.J. (deposition date: 2006-07-26, release date: 2006-09-05, Last modification date: 2020-07-29)

• Primary citation: Russell, R.J.,Haire, L.F.,Stevens, D.J.,Collins, P.J.,Lin, Y.P.,Blackburn, G.M.,Hay, A.J.,Gamblin, S.J.,Skehel, J.J.; The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.; Nature, 443:45-49, 2006; PubMed: 16915235; DOI: 10.1038/nature05114

Experimental method

X-RAY DIFFRACTION (3.5 Å)