2HTQ

N8 neuraminidase in complex with zanamivir

Summary for 2HTQ

Related2HT5 2HT7 2HT8 2HTR 2HTU 2HTV 2HTW 2HTY 2HU0 2HU4
DescriptorNeuraminidase, ZANAMIVIR (3 entities in total)
Functional Keywordsn8, neuraminidase, zanamivir, hydrolase
Biological sourceInfluenza A virus
Cellular locationVirion membrane (By similarity) Q07599
Total number of polymer chains1
Total molecular weight43489.83
Authors
Russell, R.J.,Haire, L.F.,Stevens, D.J.,Collins, P.J.,Lin, Y.P.,Blackburn, G.M.,Hay, A.J.,Gamblin, S.J.,Skehel, J.J. (deposition date: 2006-07-26, release date: 2006-09-05, Last modification date: 2011-07-13)
Primary citation
Russell, R.J.,Haire, L.F.,Stevens, D.J.,Collins, P.J.,Lin, Y.P.,Blackburn, G.M.,Hay, A.J.,Gamblin, S.J.,Skehel, J.J.
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443:45-49, 2006
PubMed: 16915235 (PDB entries with the same primary citation)
DOI: 10.1038/nature05114
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.223515.5%9.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution