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2HMR

Solution structure of reduced interstrand cross-link arising from S-alpha-methyl-gamma-OH-1,N2-propano-2'-deoxyguanosine in the 5'-CpG-3' DNA sequence

Summary for 2HMR
Entry DOI10.2210/pdb2hmr/pdb
Related2HLI 2HMD
DescriptorDNA dodecamer with interstrand cross-link (2 entities in total)
Functional Keywordscrotonaldehyde interstrand dna cross-link, dna
Total number of polymer chains2
Total formula weight7382.89
Authors
Cho, Y.-J.,Kozekov, I.D.,Harris, T.M.,Rizzo, C.J.,Stone, M.P. (deposition date: 2006-07-11, release date: 2007-03-13, Last modification date: 2022-03-09)
Primary citationCho, Y.-J.,Kozekov, I.D.,Harris, T.M.,Rizzo, C.J.,Stone, M.P.
Stereochemistry Modulates the Stability of Reduced Interstrand Cross-Links Arising from R- and S-alpha-CH(3)-gamma-OH-1,N(2)-Propano-2'-deoxyguanosine in the 5'-CpG-3' DNA Sequence
Biochemistry, 46:2608-2621, 2007
Cited by
PubMed: 17305317
DOI: 10.1021/bi061381h
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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