2HKK
Carbonic anhydrase activators: Solution and X-ray crystallography for the interaction of andrenaline with various carbonic anhydrase isoforms
Summary for 2HKK
Entry DOI | 10.2210/pdb2hkk/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | carbonic anhydrase, activators, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29738.27 |
Authors | Temperini, C.,Innocenti, A.,Vullo, D.,Scozzafava, A.,Supuran, C.T. (deposition date: 2006-07-05, release date: 2007-05-22, Last modification date: 2023-08-30) |
Primary citation | Temperini, C.,Innocenti, A.,Scozzafava, A.,Mastrolorenzo, A.,Supuran, C.T. Carbonic anhydrase activators: L-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV. Bioorg.Med.Chem.Lett., 17:628-635, 2007 Cited by PubMed: 17127057DOI: 10.1016/j.bmcl.2006.11.027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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